STOP works locally — on all sides of the trafficking chain — with an international network of Field Offices and Support Centers. The New York City headquarters coordinates all regional work. With professional psychologists and trafficking experts on staff, STOP's Support Centers provide victims with immediate access to medical and psychological services.

Initially, STOP will simultaneously open a Field Office in Bosnia and Herzegovina, and Support Centers in the regional countries from which victims are being abducted, including Moldova, Ukraine and Romania. Once operations are underway in this region, STOP will expand to West Africa and South East Asia.